Run to Live follows two Tarahumara brothers with a spiritual bond, pursuing their goal to become the world's best ultramarathon runners. However, these goals shatter when they are forcibly recruited as drug runners by a dangerous drug cartel. The story of these brothers, who face risking their families and must unite to finally take control of their destiny, captivates the viewer's interest. The film invites its viewers into the world of the Tarahumara brothers, to admire their running abilities and resilience while also feeling their pain and struggles. The film was shot in Mexico's Tarahumara region.